For the Wii
I haven't gotten too far. The story doesn't really mean much, and is weak, in my opinion, so far. But the myriad ways you can smash a zombie is great. The drill is great, you can skewer a zombie and it spins on the drill bit, knocking down anything the legs, arms and head come in contact with.
Best moment so far: go into a women's clothing store and change your clothes.